” Studies examining the effect of cannabinoid-based drugs on immunity have shown that many cellular and cytokine mechanisms are modulated by these agents, thus raising the hypothesis that these compounds may be of value in the management of chronic inflammatory diseases. The special properties of endocannabinoids as neurotransmitters, their pleiotropic effects and the impact on immune function show that the endocannabinoid system represents a revolving plate of neural and immune interactions. In this paper, we outline current information on immune effects of cannabinoids in health and disease.”
Tanasescu, R., Gran, B., & Constantinescu, C. S. (2012). The endocannabinoid system: A revolving plate in neuro-immune interaction in health and disease. Amino Acids, 45(1), 95-112. doi:10.1007/s00726-012-1252-8