Tag Archives: Multiple Sclerosis
Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering Microbiota
“Intermittent fasting increases gut microbial diversity, alters their composition and metabolic pathways”
Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease
“Our study provides evidence that the administration of gut commensals may regulate a systemic immune response and may, therefore, have a possible role in treatment strategies for MS.”
Resistance training may slow down the progression of multiple sclerosis
“Prior to and following the six-month period, the test subjects had their brains MR-scanned, and the researchers could see that there was a tendency for the brain to shrink less in those patients who undertook resistance training.”
Patients with multiple sclerosis may benefit from over-the-counter therapy
“an OHSU pilot study suggests over-the-counter antioxidant lipoic acid holds promise in improving patients’ lives.”
Nonpharmacologic Intervention Improves Mood and Cognitive Function in People with Multiple Sclerosis
“A modified Paleolithic diet, exercise, EStim, and stress management intervention like this one has the potential to improve the mood and cognitive symptoms that can lead to considerable suffering in people with MS, potentially improving quality of life and function for people with progressive MS.”
Brain microbiota disruption within demyelinating lesions in MS
“inflammatory demyelination is linked to an organ-specific dysbiosis in MS that could contribute to underlying disease mechanisms.”
Microbe changes in patients with multiple sclerosis found
“A team of researchers with Brigham and Women’s Hospital at Harvard Medical School has discovered that people with multiple sclerosis appear to have differences in their gut biome than the rest of the population.”
The endocannabinoid system: A revolving plate in neuro-immune interaction in health and disease (2012)
” Studies examining the effect of cannabinoid-based drugs on immunity have shown that many cellular and cytokine mechanisms are modulated by these agents, thus raising the hypothesis that these compounds may be of value in the management of chronic inflammatory diseases. The special properties of endocannabinoids as neurotransmitters, their pleiotropic effects and the impact on […]
Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis (1989)
“as THC has been shown to inhibit both clinical and histologic [experimental autoimmune encephalomyelitis], it may prove to be a new and relatively innocuous agent for the treatment of immune-mediated diseases.” Lyman, W. D., Sonett, J. R., Brosnan, C. F., Elkin, R., & Bornstein, M. B. (1989). Δ9-Tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis. […]
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation (2011)
“Treatment with CBD during disease onset ameliorated the severity of the clinical signs of [experimental autoimmune encephalomyelitis]. This effect of CBD was accompanied by diminished axonal damage and inflammation as well as microglial activation and T-cell recruitment in the spinal cord of MOG-injected mice. Moreover, CBD inhibited MOG-induced T-cell proliferation in vitro at both low […]