Nutrition
Ames: Vitamin and Mineral Inadequacy Accelerates Aging-associated Disease
“The triage theory posits that some functions of micronutrients are restricted during shortage and that functions required for short-term survival take precedence over those that are less essential. Insidious changes accumulate as a consequence of restriction”
Food allergies reversed in mice by targeting the microbiome
A press release from the American Chemical Society states: “A bacterial compound called butyrate that’s made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it’s nasty to take orally. Today, scientists describe a more palatable way to deliver this compound and report that their “polymeric micelles” are effective against peanut […]
Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease
“After summarizing the collected information from the current studies, our review concluded that food additives exert multiple effects on gut microbiota and intestinal homeostasis, which may be associated with the onset and progression of IBD. Furthermore, food additives also remarkably mediated the alterations of bacterial functions.”
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
“Intermittent fasting changes the gut bacteria activity of mice and increases their ability to recover from nerve damage. The new research is published in Nature and was conducted by Imperial College London researchers. They observed how fasting led to the gut bacteria increasing production of a metabolite known as 3-Indolepropionic acid (IPA), which is required for regenerating nerve fibers […]
Sulforaphane exhibits antiviral activity against SARS-CoV-2 in vitro and in mice
“We determined that SFN has potent antiviral activity against HCoV-OC43 and multiple strains of SARS-CoV-2, including Delta and Omicron … “we documented that SFN can inhibit in vitro and in vivo replication of SARS-CoV-2 at pharmacologically and potentially therapeutically achievable concentrations. Further, it can modulate the inflammatory response, thereby decreasing the consequences of infection in […]
The Metabolic Role and Therapeutic Potential of the Microbiome
Here we discuss how the gut bacterial composition is altered in, and can contribute to, cardiometabolic disease, as well as how the gut bacteria can be targeted to treat and prevent metabolic diseases.
How zinc boosts the immune system
In mice, mineral improves regeneration of key immune organ and immune-cell recovery after bone marrow transplant
Supplement appears to boost muscle, mitochondria health
New research suggests that the supplement, urolithin A, may help improve or prolong muscle activity in people who are aging or who have diseases that make exercise difficult.
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
“Vitamin D supplementation for five years, with or without omega 3 fatty acids, reduced autoimmune disease by 22%, while omega 3 fatty acid supplementation with or without vitamin D reduced the autoimmune disease rate by 15% (not statistically significant). Both treatment arms showed larger effects than the reference arm (vitamin D placebo and omega 3 […]
High-sucrose diets contribute to psychosis-related higher brain dysfunctions in mice
“Here, we demonstrate that a high-sucrose diet during adolescence induces psychosis-related behavioral endophenotypes, including hyperactivity, poor working memory, impaired sensory gating, and disrupted interneuron function in mice deficient for glyoxalase-1 (GLO1), an enzyme involved in detoxification of sucrose metabolites. Furthermore, the high-sucrose diet induced microcapillary impairments and reduced brain glucose uptake in brains of Glo1-deficient mice.”