Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation (2011)

“Treatment with CBD during disease onset ameliorated the severity of the clinical signs of [experimental autoimmune encephalomyelitis]. This effect of CBD was accompanied by diminished axonal damage and inflammation as well as microglial activation and T-cell recruitment in the spinal cord of MOG-injected mice. Moreover, CBD inhibited MOG-induced T-cell proliferation in vitro at both low and high concentrations of the myelin antigen.”

Kozela, E., Lev, N., Kaushansky, N., Eilam, R., Rimmerman, N., Levy, R., … Vogel, Z. (2011). Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice. British Journal of Pharmacology, 163(7), 1507-1519.

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