The role of the gut microbiota in multiple sclerosis
“In this Review, we examine the influence that the gut microbiota have on immune function via modulation of serotonin production in the gut and through complex interactions with components of the immune system, such as T cells and B cells. We then present evidence from studies in mice and humans that these effects of the […]
Scientists identify gut-derived metabolites that play a role in neurodegeneration (2021)
“Our findings suggest that MS patients’ gut bacteria produce and release large amounts p-cresol-sulfate, indoxyl-sulfate and N-phenylacetylglutamine into the bloodstream, and they eventually reach the cerebrospinal fluid,” said Hye-Jin Park, one of the lead authors on the study and a research associate with the Neuroscience Initiative at the Advanced Science Research Center at the Graduate […]
COVID-19 Microbiota
11 JAN 2021: Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19 (Gut)“Associations between gut microbiota composition, levels of cytokines and inflammatory markers in patients with COVID-19 suggest that the gut microbiome is involved in the magnitude of COVID-19 severity possibly via modulating host immune responses. Furthermore, the gut microbiota […]
New evidence hints at the role of gut microbiota in autistic spectrum disorder
“recent neuroscience studies have found that the biological makeup of the gut could contribute to some of the most characteristic symptoms of ASD. More specifically, experiments on mice suggest that the pathway between gut bacteriaand the central nervous system can affect social behaviors.”…“The recent findings gathered by this team of researchers seem to confirm previous […]
It’s not Tourette’s but a new type of mass sociogenic illness
“Over the past 2 years, a remarkably high number of young patients have been referred to our specialized Tourette outpatient clinic presenting with symptoms closely resembling the ones Jan Zimmermann shows in his videos. All these patients had been prediagnosed with Tourette syndrome, even partly as treatment-resistant Tourette syndrome after having received pharmacotherapy with different […]
Phages Treat Gut Inflammation in Mice
“Phase 2 clinical trial to evaluate the effectiveness of using a phage mixture to treat IBD in humans has been approved but not yet started, says Elinav, who cofounded a company seeking to commercialize phage treatments. The study authors conclude that in addition to the prospect of leading to a generalized therapy, their results indicate […]
Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease
“After summarizing the collected information from the current studies, our review concluded that food additives exert multiple effects on gut microbiota and intestinal homeostasis, which may be associated with the onset and progression of IBD. Furthermore, food additives also remarkably mediated the alterations of bacterial functions.”
Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders
“Collectively, these results show for the first time that glyphosate infiltrates the brain, elevates both the expression of TNFα and soluble Aβ, and disrupts the transcriptome in a dose-dependent manner, suggesting that exposure to this herbicide may have detrimental outcomes regarding the health of the general population”
The serotonin theory of depression: a systematic umbrella review of the evidence
“The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations. Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.”
Research Suggests Restoring Lost Bacterial Cues Might Protect against T1D
“In the case of T1D, decreased gut microbiome diversity is characteristic of and can be predictive of disease onset, suggesting that at-risk children may be missing specific microbes with disease-mitigating functions,” Hill wrote. The team further suggested in their essay that fortification of these microbial activities in children who carry risk alleles for T1D could […]