COVID-19 Immunity
Updated October 20, 2021
Bifidobacteria-mediated immune system imprinting early in life
“Here we show that a lack of bifidobacteria, and in particular depletion of genes required for human milk oligosaccharide (HMO) utilization from the metagenome, is associated with systemic inflammation and immune dysregulation early in life”
Microbiota from Young Mice Improve Cognitive Function in Older Recipients
“Conducting fecal microbial transplants from young mice to old mice, researchers were able to show a reversal of aging-associated differences and a slowing of cognitive impairments.”
Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression
Exposing newborn mice to low-dose penicillin led to substantial changes in intestinal microbiota population structure and composition. Transcriptomic alterations implicate pathways perturbed in neurodevelopmental and neuropsychiatric disorders. There also were substantial effects on frontal cortex and amygdala gene expression by bioinformatic interrogation, affecting multiple pathways underlying neurodevelopment.
A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases
“The lack of a comprehensive database for human-associated viruses has historically stymied efforts to interrogate the impact of the virome on human health. This study probes thousands of datasets to uncover sequences from over 45,000 unique virus taxa, with historically high per-genome completeness. Large publicly available case-control studies are reanalyzed, and over 2,200 strong virus–disease […]
COVID-19 Obesity
Updated Apr 29, 2021
COVID-19 Neuro
Updated Aug 29, 2020
COVID-19 Pulmonary / Cardiac
Updated Oct 9, 2021
Walden-Labs: Solutions for Self-Reliance
Collection of articles written by John Robb
COVID-19 Literature III
literature published 1 May 2020 – present Updated Sep 10, 2020