Microplastics ingested orally accumulate in the brain
A joint research team at the Division of Biotechnology, DGIST, confirmed that microplastics(MPs) ingested orally accumulate in the brain and act as neurotoxic substances.
Debaryomyces is enriched in Crohn’s disease intestinal tissue and impairs healing in mice
“The salt-tolerant fungus Debaryomyces hansenii, used in the food industry for surface ripening cheese and meat products, is enriched in the inflamed mucosal tissues of patients with Crohn’s disease and leads to impaired wound healing in mice”
Mouse Study Reveals Subset of Immune Cells May Promote Inflammation in Multiple Sclerosis
“Collectively, our data define a population of inflammatory ILC3s that is essential for directly promoting T-cell-dependent neuroinflammation in the CNS and reveal the potential of harnessing peripheral tissue-resident ILC3s for the prevention of autoimmune disease,” concluded the researchers.
Researchers study the link between vitamin D and inflammation
“Our work demonstrates a mechanism by which vitamin D reduces inflammation caused by T cells. These are important cells of the immune system and implicated as part of the immune response to the infection causing COVID-19.”
SARS-CoV-2: Chronic Infection and Variants of Concern
3 DEC 2020: Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host (NEJM)“Phylogenetic analysis was consistent with persistent infection and accelerated viral evolution. Amino acid changes were predominantly in the spike gene and the receptor-binding domain, which make up 13% and 2%” 5 FEB 2021: SARS-CoV-2 evolution during treatment of chronic infection (Nature)“These data reveal […]
Ubiquitous food additive alters human microbiota and intestinal environment
New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.
Gut Bacteria May Point to Early Detection of Colon Cancer
“New research (from University of Washington School of Medicine) suggests that the presence of certain bacteria in a gut biome may be an indicator of colon polyps that will become cancerous.”
Phthalate and novel plasticizer concentrations in food items from U.S. fast food chains: a preliminary analysis
“… these are the first measurements of DEHT in food. Our preliminary findings suggest that ortho-phthalates remain ubiquitous and replacement plasticizers may be abundant in fast food meals.”
Effect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation
“In RCTs examining cardiovascular outcomes, marine omega-3 supplementation was associated with an increased risk of AF. The risk appeared to be greater in trials testing >1g/d.”
Transmission of trained immunity and heterologous resistance to infections across generations
“Here we provide evidence for transmission of trained immunity across generations to murine progeny that survived a sublethal systemic infection with Candida albicans or a zymosan challenge. The progeny of trained mice exhibited cellular, developmental, transcriptional and epigenetic changes associated with the bone marrow-resident myeloid effector and progenitor cell compartment. Moreover, the progeny of trained mice showed […]