Strict diet combats rare progeria aging disorders in mice

Posted on by WOCredentials
“The study has now established that in mice with this disease it is actually very important to eat less. ‘Mice that were given 30 percent less food lived for more than a year, compared to only 4 to 6 months if they were not put on a diet. The rapid deterioration of the nervous system, retina and motor coordination were practically stopped. The liver, kidneys, bones, immune system, and vascular system remained in a much healthier state’, says researcher Martijn Dollé from RIVM. ‘This also provides possibilities to investigate other interventions counteracting aging-related complications.'”

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W. P. Vermeij et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice, Nature (2016). DOI: 10.1038/nature19329

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