“A modified Paleolithic diet, exercise, EStim, and stress management intervention like this one has the potential to improve the mood and cognitive symptoms that can lead to considerable suffering in […]
Tag: Multiple Sclerosis
Brain microbiota disruption within demyelinating lesions in MS
“inflammatory demyelination is linked to an organ-specific dysbiosis in MS that could contribute to underlying disease mechanisms.”
Microbe changes in patients with multiple sclerosis found
“A team of researchers with Brigham and Women’s Hospital at Harvard Medical School has discovered that people with multiple sclerosis appear to have differences in their gut biome than the […]
The endocannabinoid system: A revolving plate in neuro-immune interaction in health and disease (2012)
” Studies examining the effect of cannabinoid-based drugs on immunity have shown that many cellular and cytokine mechanisms are modulated by these agents, thus raising the hypothesis that these compounds […]
Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis (1989)
“as THC has been shown to inhibit both clinical and histologic [experimental autoimmune encephalomyelitis], it may prove to be a new and relatively innocuous agent for the treatment of immune-mediated […]
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation (2011)
“Treatment with CBD during disease onset ameliorated the severity of the clinical signs of [experimental autoimmune encephalomyelitis]. This effect of CBD was accompanied by diminished axonal damage and inflammation as […]
Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype (2013)
“Here we show that the main psychoactive cannabinoid, Δ-9-tetrahydrocannabinol (THC), and the main nonpsychoactive cannabinoid, cannabidiol (CBD), markedly reduce the Th17 phenotype which is known to be increased in inflammatory […]
Fasting-like diet reduces multiple sclerosis symptoms
“During the fasting-mimicking diet, cortisone is produced and that initiates a killing of autoimmune cells,” said Valter Longo, the study’s lead author and professor who directs the USC Longevity Institute […]
MS Microbiome Connection
“New research by investigators at Brigham and Women’s Hospital (BWH) suggests that bacteria living in the gut may remotely influence the activity of cells in the brain that are involved […]