Phages Treat Gut Inflammation in Mice

“Phase 2 clinical trial to evaluate the effectiveness of using a phage mixture to treat IBD in humans has been approved but not yet started, says Elinav, who cofounded a company seeking to commercialize phage treatments. The study authors conclude that in addition to the prospect of leading to a generalized therapy, their results indicate the potential to analyze the microbiomes of individuals and tailor specific phage cocktails to treat their illnesses.

Describing this work as proof of concept, Elinav says he hopes that eventually an approach like that laid out in the new paper could be used to identify bacteria associated with a wide range of diseases—such as obesity, type 2 diabetes, cancer, and even neurodegeneration—in order to develop phage therapies to target them.”

Read article from The Scientist here: