Gut microbes contribute to age-associated inflammation (mouse study)

“gut microbes are one of the culprits behind age-associated inflammation and premature death in mice. Imbalances in the composition of gut microbes in older mice cause the intestines to become leaky, allowing the release of bacterial products that trigger inflammation and impair immune function.”

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Cell Host & Microbe, Thevaranjan and Puchta et al.: “Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation and macrophage dysfunction” www.cell.com/cell-host-microbe … 1931-3128(17)30112-9 DOI: 10.1016/j.chom.2017.03.002