“The findings indicate that electrical signals in the vagus nerve activate a cholinergic signal promoting Alox15-dependent lipid mediator biosynthesis and accelerating resolution of inflammation, providing additional insights into neural regulation of inflammation.”
Read PNAS paper published 27 May 2022 here: https://doi.org/10.1073/pnas.2023285119
A.S. Caravaca, A.L. Gallina, L. Tarnawski, V.S. Shavva, R.A. Colas, J. Dalli, S.G. Malin, H. Hult, H. Arnardottir, P.S. Olofsson, Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit, Proc. Natl. Acad. Sci. U.S.A.
119 (22) e2023285119,
https://doi.org/10.1073/pnas.2023285119 (2022).