Tag Archives: Neuro
Cognitive Impact of Reduced Sun Exposure During Pandemic
Could reduced prenatal sun exposure be related to lowered cognitive ability in pandemic babies?
Food allergies reversed in mice by targeting the microbiome
A press release from the American Chemical Society states: “A bacterial compound called butyrate that’s made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it’s nasty to take orally. Today, scientists describe a more palatable way to deliver this compound and report that their “polymeric micelles” are effective against peanut […]
The role of the gut microbiota in multiple sclerosis
“In this Review, we examine the influence that the gut microbiota have on immune function via modulation of serotonin production in the gut and through complex interactions with components of the immune system, such as T cells and B cells. We then present evidence from studies in mice and humans that these effects of the […]
Scientists identify gut-derived metabolites that play a role in neurodegeneration (2021)
“Our findings suggest that MS patients’ gut bacteria produce and release large amounts p-cresol-sulfate, indoxyl-sulfate and N-phenylacetylglutamine into the bloodstream, and they eventually reach the cerebrospinal fluid,” said Hye-Jin Park, one of the lead authors on the study and a research associate with the Neuroscience Initiative at the Advanced Science Research Center at the Graduate […]
New evidence hints at the role of gut microbiota in autistic spectrum disorder
“recent neuroscience studies have found that the biological makeup of the gut could contribute to some of the most characteristic symptoms of ASD. More specifically, experiments on mice suggest that the pathway between gut bacteriaand the central nervous system can affect social behaviors.”…“The recent findings gathered by this team of researchers seem to confirm previous […]
Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders
“Collectively, these results show for the first time that glyphosate infiltrates the brain, elevates both the expression of TNFα and soluble Aβ, and disrupts the transcriptome in a dose-dependent manner, suggesting that exposure to this herbicide may have detrimental outcomes regarding the health of the general population”
The serotonin theory of depression: a systematic umbrella review of the evidence
“The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations. Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.”
Blood-brain barrier breakdown is an early biomarker for human cognitive dysfunction (2019)
Our data show that individuals with early cognitive dysfunction develop brain capillary damage and BBB breakdown in the hippocampus irrespective of Alzheimer’s Aβ and/or tau biomarker changes, suggesting that BBB breakdown is an early biomarker of human cognitive dysfunction independent of Aβ and tau.
Decoding a direct dialog between the gut microbiota and the brain
“It is extraordinary to discover that bacterial fragments act directly on a brain center as strategic as the hypothalamus, which is known to manage vital functions such as body temperature, reproduction, hunger and thirst,” comments Pierre-Marie Lledo, CNRS scientist and Head of the Institut Pasteur’s Perception and Memory Unit.”
Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and AE after HPV Vaccination?
“We highlight the role of three mechanisms—autoimmunity, neuroinflammation, and small fiber neuropathy—in the pathogenesis of the disease [fibromyalgia].”