“during periods of disease activity people with IBD had higher levels of polyunsaturated fatty acids, including adrenate and arachidonate. The researchers also discovered that nicotinuric acid was found almost exclusively in the stool of patients with IBD and that levels of vitamins B5 and B3 were particularly depleted in the gut of people with IBD.”
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Paper: https://www.nature.com/articles/s41586-019-1237-9
Lloyd-Price, J., Arze, C., Ananthakrishnan, A.N. et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature 569, 655–662 (2019). https://doi.org/10.1038/s41586-019-1237-9