Chemical transformation of xenobiotics by the human gut microbiota

“The microorganisms that inhabit the human gut alter the chemical structures of ingested compounds, including dietary components, industrial chemicals, and drugs. These changes affect xenobiotic toxicity, biological activity, and bioavailability. The gut microbial enzymes responsible for many of these transformations are poorly understood.”

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Nitzan Koppel et al.,Chemical transformation of xenobiotics by the human gut microbiota.Science356,eaag2770(2017).DOI:10.1126/science.aag2770