“Here we provide evidence for transmission of trained immunity across generations to murine progeny that survived a sublethal systemic infection with Candida albicans or a zymosan challenge. The progeny of trained mice […]
Category: Science
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
“The inflammatory process causes the gut vascular barrier to become more permeable, resulting in the spread of inflammation beyond the intestine, while the vascular barrier in the choroid plexus shuts […]
COVID-19 Immunity
Updated May 25, 2024
Bifidobacteria-mediated immune system imprinting early in life
“Here we show that a lack of bifidobacteria, and in particular depletion of genes required for human milk oligosaccharide (HMO) utilization from the metagenome, is associated with systemic inflammation and […]
Microbiota from Young Mice Improve Cognitive Function in Older Recipients
“Conducting fecal microbial transplants from young mice to old mice, researchers were able to show a reversal of aging-associated differences and a slowing of cognitive impairments.”
Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression
Exposing newborn mice to low-dose penicillin led to substantial changes in intestinal microbiota population structure and composition. Transcriptomic alterations implicate pathways perturbed in neurodevelopmental and neuropsychiatric disorders. There also were […]
A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases
“The lack of a comprehensive database for human-associated viruses has historically stymied efforts to interrogate the impact of the virome on human health. This study probes thousands of datasets to […]
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes
“Here, we summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease.”
COVID-19 Obesity
Updated January 24, 2022
COVID-19 Supply Chain News
updated June 25, 2020