“Here, we summarize the important data on vitamin D, including polymorphisms in genes related to vitamin D metabolism, EBV and ERV, in the pathogenesis of MS and create hypotheses regarding […]
Category: Neuroscience
Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and AE after HPV Vaccination?
“We highlight the role of three mechanisms—autoimmunity, neuroinflammation, and small fiber neuropathy—in the pathogenesis of the disease [fibromyalgia].”
High-sucrose diets contribute to psychosis-related higher brain dysfunctions in mice
“Here, we demonstrate that a high-sucrose diet during adolescence induces psychosis-related behavioral endophenotypes, including hyperactivity, poor working memory, impaired sensory gating, and disrupted interneuron function in mice deficient for glyoxalase-1 […]
Research finds potential mechanism linking autism, intestinal inflammation
“When a mother experiences an infection during pregnancy and her immune system produces elevated levels of the molecule Interleukin-17a (IL-17a), that can not only alter brain development in her fetus, […]
Microplastics ingested orally accumulate in the brain
A joint research team at the Division of Biotechnology, DGIST, confirmed that microplastics(MPs) ingested orally accumulate in the brain and act as neurotoxic substances.
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
“The inflammatory process causes the gut vascular barrier to become more permeable, resulting in the spread of inflammation beyond the intestine, while the vascular barrier in the choroid plexus shuts […]
Microbiota from Young Mice Improve Cognitive Function in Older Recipients
“Conducting fecal microbial transplants from young mice to old mice, researchers were able to show a reversal of aging-associated differences and a slowing of cognitive impairments.”
Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression
Exposing newborn mice to low-dose penicillin led to substantial changes in intestinal microbiota population structure and composition. Transcriptomic alterations implicate pathways perturbed in neurodevelopmental and neuropsychiatric disorders. There also were […]
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes
“Here, we summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease.”
Aluminum and Amyloid-β in Familial Alzheimer’s Disease
“we have obtained brain tissues from a Colombian cohort of donors with familial Alzheimer’s disease. We have used established methods to measure the aluminum content of these tissues and we […]