“In this Review, we examine the influence that the gut microbiota have on immune function via modulation of serotonin production in the gut and through complex interactions with components of […]
Tag: Multiple Sclerosis
Scientists identify gut-derived metabolites that play a role in neurodegeneration (2021)
“Our findings suggest that MS patients’ gut bacteria produce and release large amounts p-cresol-sulfate, indoxyl-sulfate and N-phenylacetylglutamine into the bloodstream, and they eventually reach the cerebrospinal fluid,” said Hye-Jin Park, […]
Study identifies how Epstein-Barr virus triggers multiple sclerosis
“Part of the EBV protein mimics your own host protein—in this case, GlialCAM, found in the insulating sheath on nerves,” said William Robinson, MD, Ph.D., professor of immunology and rheumatology […]
Vitamin D, Epstein-Barr virus, and endogenous retroviruses in multiple sclerosis – facts and hypotheses (2021)
“Here, we summarize the important data on vitamin D, including polymorphisms in genes related to vitamin D metabolism, EBV and ERV, in the pathogenesis of MS and create hypotheses regarding […]
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
“The team analyzed serum samples taken biennially by the military and determined the soldiers’ EBV status at time of first sample and the relationship between EBV infection and MS onset […]
Mouse Study Reveals Subset of Immune Cells May Promote Inflammation in Multiple Sclerosis
“Collectively, our data define a population of inflammatory ILC3s that is essential for directly promoting T-cell-dependent neuroinflammation in the CNS and reveal the potential of harnessing peripheral tissue-resident ILC3s for […]
Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering Microbiota
“Intermittent fasting increases gut microbial diversity, alters their composition and metabolic pathways”
Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease
“Our study provides evidence that the administration of gut commensals may regulate a systemic immune response and may, therefore, have a possible role in treatment strategies for MS.”
Resistance training may slow down the progression of multiple sclerosis
“Prior to and following the six-month period, the test subjects had their brains MR-scanned, and the researchers could see that there was a tendency for the brain to shrink less […]
Patients with multiple sclerosis may benefit from over-the-counter therapy
“an OHSU pilot study suggests over-the-counter antioxidant lipoic acid holds promise in improving patients’ lives.”