A press release from the American Chemical Society states: “A bacterial compound called butyrate that’s made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it’s […]
Tag: Inflammatory Bowel Disease
Phages Treat Gut Inflammation in Mice
“Phase 2 clinical trial to evaluate the effectiveness of using a phage mixture to treat IBD in humans has been approved but not yet started, says Elinav, who cofounded a […]
Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease
“After summarizing the collected information from the current studies, our review concluded that food additives exert multiple effects on gut microbiota and intestinal homeostasis, which may be associated with the […]
Key growth factor protects gut from inflammatory bowel disease
In their study, published Jan. 31 in Nature Immunology, the researchers found that the growth factor, HB-EGF, is produced in response to gut inflammation by a set of immune-regulating cells called […]
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
“The inflammatory process causes the gut vascular barrier to become more permeable, resulting in the spread of inflammation beyond the intestine, while the vascular barrier in the choroid plexus shuts […]
Mitochondrial dysfunction in Crohn’s disease
“Many studies have revealed the involvement of mitochondrial stress in the pathophysiology of IBD but whether this is a cause or consequence of the disease is not known,”
The diet-microbiome connection in inflammatory bowel disease
“The authors say the findings offer hope for better dietary therapies for IBD, perhaps ones that deliver “good” bacteria such as C. scindens or C. hiranonis while suppressing disease-associated species.”
Frying oil consumption worsened colon cancer and colitis in mice
“Food scientists have shown that feeding frying oil to mice exaggerated colonic inflammation, enhanced tumor growth and worsened gut leakage, spreading bacteria or toxic bacterial products into the bloodstream.”
Human Microbiome Project reveals how microbiome is disrupted during IBD
“during periods of disease activity people with IBD had higher levels of polyunsaturated fatty acids, including adrenate and arachidonate. The researchers also discovered that nicotinuric acid was found almost exclusively […]