How the microbiome may affect mental illness and interact with treatment

“the diversity of microorganisms living in the gastrointestinal system were measured while rats were subjected to chronic stress over a 7-week period. Not only did the number of microorganisms decrease as stress became more chronic, behavioral changes suggested that the rats also began experiencing loss of pleasure and “despair-like” behavior.”

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Emily Jutkiewicz. Gut Microbial Community and Behavioral Changes in a Chronic Mild Stress Model of Depression in Rats. Neuropsychopharmacology, 2016 DOI: 10.1038/npp.2016.239