“Researchers have discovered that a powerful guardian gene known to protect against a variety of autoimmune diseases, including type 1 diabetes, is triggered by the bacteria in our gut. This finding offers a clue to the complex interaction between our genes, immune system and gut microbiota.”
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M. Silverman, L. Kua, A. Tanca, M. Pala, A. Palomba, C. Tanes, K.Bittinger, S. Uzzau, C. Benoist, D. Mathis, Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny, Proc. Natl. Acad. Sci. U.S.A.114 (36) 9671-9676, https://doi.org/10.1073/pnas.1712280114 (2017).