Dengue Vaccine Program Halted Over Safety Issues

Two studies have suggested that for children who haven’t been exposed to dengue before vaccination, Dengvaxia, the drug made by France-based pharmaceutical company Sanofi, can actually increase the likelihood of hospitalization for the disease”

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Neil M. Ferguson et al.,Benefits and risks of the Sanofi-Pasteur dengue vaccine: Modeling optimal deployment.Science353,1033-1036(2016).DOI:10.1126/science.aaf9590

Halstead SB, Russell PK. Protective and immunological behavior of chimeric yellow fever dengue vaccine. Vaccine. 2016 Mar 29;34(14):1643-7. doi: 10.1016/j.vaccine.2016.02.004. Epub 2016 Feb 10. PMID: 26873054.