“In the case of T1D, decreased gut microbiome diversity is characteristic of and can be predictive of disease onset, suggesting that at-risk children may be missing specific microbes with disease-mitigating […]
Author: ContraReport
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
“Intermittent fasting changes the gut bacteria activity of mice and increases their ability to recover from nerve damage. The new research is published in Nature and was conducted by Imperial College London […]
The occurrence of hyperactivated platelets and fibrinaloid microclots in ME/CFS
(preprint) “We conclude that ME/CFS is accompanied by substantial and measurable changes in coagulability, platelet hyperactivation, and fibrinaloid microclot formation. … Fibrinaloid microclots, in particular can provide a ready explanation, […]
Blood-brain barrier breakdown is an early biomarker for human cognitive dysfunction (2019)
Our data show that individuals with early cognitive dysfunction develop brain capillary damage and BBB breakdown in the hippocampus irrespective of Alzheimer’s Aβ and/or tau biomarker changes, suggesting that BBB […]
Vagus nerve stimulation promotes resolution of inflammation
“The findings indicate that electrical signals in the vagus nerve activate a cholinergic signal promoting Alox15-dependent lipid mediator biosynthesis and accelerating resolution of inflammation, providing additional insights into neural regulation […]
COVID-19 Liver
Updated May 24, 2024
Sulforaphane exhibits antiviral activity against SARS-CoV-2 in vitro and in mice
“We determined that SFN has potent antiviral activity against HCoV-OC43 and multiple strains of SARS-CoV-2, including Delta and Omicron … “we documented that SFN can inhibit in vitro and in […]
The Metabolic Role and Therapeutic Potential of the Microbiome
Here we discuss how the gut bacterial composition is altered in, and can contribute to, cardiometabolic disease, as well as how the gut bacteria can be targeted to treat and […]
Decoding a direct dialog between the gut microbiota and the brain
“It is extraordinary to discover that bacterial fragments act directly on a brain center as strategic as the hypothalamus, which is known to manage vital functions such as body temperature, […]
How zinc boosts the immune system
In mice, mineral improves regeneration of key immune organ and immune-cell recovery after bone marrow transplant