A microbial metabolite mediates protection against influenza infection

A recent study, led by Dr. Thaddeus Stappenbeck from the Department of Pathology and Immunology at Washington University School of Medicine (St. Louis, USA), has found that a particular gut microbe modulates immune response to influenza infection in mice through breaking down flavonoids naturally found in vegetable foods.

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Ashley L. Steed et al.,The microbial metabolite desaminotyrosine protects from influenza through type I interferon.Science357,498-502(2017).DOI:10.1126/science.aam5336