It’s not Tourette’s but a new type of mass sociogenic illness
“Over the past 2 years, a remarkably high number of young patients have been referred to our specialized Tourette outpatient clinic presenting with symptoms closely resembling the ones Jan Zimmermann shows in his videos. All these patients had been prediagnosed with Tourette syndrome, even partly as treatment-resistant Tourette syndrome after having received pharmacotherapy with different […]
Phages Treat Gut Inflammation in Mice
“Phase 2 clinical trial to evaluate the effectiveness of using a phage mixture to treat IBD in humans has been approved but not yet started, says Elinav, who cofounded a company seeking to commercialize phage treatments. The study authors conclude that in addition to the prospect of leading to a generalized therapy, their results indicate […]
Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease
“After summarizing the collected information from the current studies, our review concluded that food additives exert multiple effects on gut microbiota and intestinal homeostasis, which may be associated with the onset and progression of IBD. Furthermore, food additives also remarkably mediated the alterations of bacterial functions.”
Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders
“Collectively, these results show for the first time that glyphosate infiltrates the brain, elevates both the expression of TNFα and soluble Aβ, and disrupts the transcriptome in a dose-dependent manner, suggesting that exposure to this herbicide may have detrimental outcomes regarding the health of the general population”
The serotonin theory of depression: a systematic umbrella review of the evidence
“The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations. Some evidence was consistent with the possibility that long-term antidepressant use reduces serotonin concentration.”
Research Suggests Restoring Lost Bacterial Cues Might Protect against T1D
“In the case of T1D, decreased gut microbiome diversity is characteristic of and can be predictive of disease onset, suggesting that at-risk children may be missing specific microbes with disease-mitigating functions,” Hill wrote. The team further suggested in their essay that fortification of these microbial activities in children who carry risk alleles for T1D could […]
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
“Intermittent fasting changes the gut bacteria activity of mice and increases their ability to recover from nerve damage. The new research is published in Nature and was conducted by Imperial College London researchers. They observed how fasting led to the gut bacteria increasing production of a metabolite known as 3-Indolepropionic acid (IPA), which is required for regenerating nerve fibers […]
The occurrence of hyperactivated platelets and fibrinaloid microclots in ME/CFS
(preprint) “We conclude that ME/CFS is accompanied by substantial and measurable changes in coagulability, platelet hyperactivation, and fibrinaloid microclot formation. … Fibrinaloid microclots, in particular can provide a ready explanation, via (temporary) blockage of microcapillaries and hence ischaemia, for many of the symptoms, such as fatigue, seen in patients with ME/CFS. The discovery of these […]
Blood-brain barrier breakdown is an early biomarker for human cognitive dysfunction (2019)
Our data show that individuals with early cognitive dysfunction develop brain capillary damage and BBB breakdown in the hippocampus irrespective of Alzheimer’s Aβ and/or tau biomarker changes, suggesting that BBB breakdown is an early biomarker of human cognitive dysfunction independent of Aβ and tau.
Vagus nerve stimulation promotes resolution of inflammation
“The findings indicate that electrical signals in the vagus nerve activate a cholinergic signal promoting Alox15-dependent lipid mediator biosynthesis and accelerating resolution of inflammation, providing additional insights into neural regulation of inflammation.”