Tag Archives: Immune
How zinc boosts the immune system
In mice, mineral improves regeneration of key immune organ and immune-cell recovery after bone marrow transplant
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers
“…these findings further explain why some individuals may be able to control HIV-1 viral loads without ART.”
Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism (2018)
“In this review, we have presented an updated prospective of the mitochondrial machinery that drives various immune responses.”
Research finds potential mechanism linking autism, intestinal inflammation
“When a mother experiences an infection during pregnancy and her immune system produces elevated levels of the molecule Interleukin-17a (IL-17a), that can not only alter brain development in her fetus, but also alter her microbiome such that after birth the newborn’s immune system can become primed for future inflammatory attacks.”
Mouse Study Reveals Subset of Immune Cells May Promote Inflammation in Multiple Sclerosis
“Collectively, our data define a population of inflammatory ILC3s that is essential for directly promoting T-cell-dependent neuroinflammation in the CNS and reveal the potential of harnessing peripheral tissue-resident ILC3s for the prevention of autoimmune disease,” concluded the researchers.
Researchers study the link between vitamin D and inflammation
“Our work demonstrates a mechanism by which vitamin D reduces inflammation caused by T cells. These are important cells of the immune system and implicated as part of the immune response to the infection causing COVID-19.”
Transmission of trained immunity and heterologous resistance to infections across generations
“Here we provide evidence for transmission of trained immunity across generations to murine progeny that survived a sublethal systemic infection with Candida albicans or a zymosan challenge. The progeny of trained mice exhibited cellular, developmental, transcriptional and epigenetic changes associated with the bone marrow-resident myeloid effector and progenitor cell compartment. Moreover, the progeny of trained mice showed […]
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes
“Here, we summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease.”
Immune cells destroy healthy brain connections, diminish cognitive function in obese mice
“Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice published in JNeurosci.”
Behavioral conditioning of immunosuppression is possible in humans.
“These data demonstrate for the first time that immunosuppression can be behaviorally conditioned in humans.”