Tag Archives: Autoimmune
Research Suggests Restoring Lost Bacterial Cues Might Protect against T1D
“In the case of T1D, decreased gut microbiome diversity is characteristic of and can be predictive of disease onset, suggesting that at-risk children may be missing specific microbes with disease-mitigating functions,” Hill wrote. The team further suggested in their essay that fortification of these microbial activities in children who carry risk alleles for T1D could […]
Study identifies how Epstein-Barr virus triggers multiple sclerosis
“Part of the EBV protein mimics your own host protein—in this case, GlialCAM, found in the insulating sheath on nerves,” said William Robinson, MD, Ph.D., professor of immunology and rheumatology at Stanford. “This means that when the immune system attacks EBV to clear the virus, it also ends up targeting GlialCAM in the myelin.”
New way viruses trigger autoimmunity discovered
“…The researchers found that the mice with gastritis had developed antibodies against proteins on stomach cells. But they also had developed antibodies against a wide array of normal proteins associated with other autoimmune conditions. In addition, they had many T cells that targeted the body’s own normal proteins, and other changes to the T cell […]
Key growth factor protects gut from inflammatory bowel disease
In their study, published Jan. 31 in Nature Immunology, the researchers found that the growth factor, HB-EGF, is produced in response to gut inflammation by a set of immune-regulating cells called ILC3s. These immune cells reside in many organs including the intestines, though their numbers are known to be depleted in the inflamed intestines of IBD […]
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
“Vitamin D supplementation for five years, with or without omega 3 fatty acids, reduced autoimmune disease by 22%, while omega 3 fatty acid supplementation with or without vitamin D reduced the autoimmune disease rate by 15% (not statistically significant). Both treatment arms showed larger effects than the reference arm (vitamin D placebo and omega 3 […]
Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and AE after HPV Vaccination?
“We highlight the role of three mechanisms—autoimmunity, neuroinflammation, and small fiber neuropathy—in the pathogenesis of the disease [fibromyalgia].”
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
“The team analyzed serum samples taken biennially by the military and determined the soldiers’ EBV status at time of first sample and the relationship between EBV infection and MS onset during the period of active duty. In this cohort, the risk of MS increased 32-fold after infection with EBV”
COVID-19 Autoimmunity
Updated July 4, 2022
Metals in Baby Teeth Could Help Reveal What Causes Autism, ADHD
“It isn’t only a story of ‘[metal] exposure leads to bad outcomes’ — it’s also a story of how different metabolic profiles may make certain people more vulnerable,”
Vitamin A regulates immune system regulation
“What’s the trick to the microbiome’s work with the immune system? Vitamin A — the bacteria moderate active vitamin A levels in the intestine, protecting the microbiome from an overactive immune response.”