“Here we provide evidence for transmission of trained immunity across generations to murine progeny that survived a sublethal systemic infection with Candida albicans or a zymosan challenge. The progeny of trained mice […]
Category: Epigenetics
Gut Microbiota Imbalance Promotes Onset of Colorectal Cancer
“A link between fecal dysbiosis (an imbalance in gut bacteria composition) and the genetic and epigenetic DNA signature in the animals’ tissues was identified using statistical tests. Mice who had […]
Scientists tie walnuts to gene expressions related to breast cancer
“a Marshall University team revealed that consumption of two ounces of walnuts a day for about two weeks significantly changed gene expression in confirmed breast cancers.”
UCLA cell study reveals how head injuries lead to serious brain diseases
The biologists found that hundreds of genes are adversely affected by mild traumatic brain injury, such as a concussion. These altered genes can later lead to Alzheimer’s, Parkinson’s and other […]
Administering hormones affects DNA
“researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor – in this case, an endogenous oestrogen – leads to epigenetic […]
Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissue
“Gut microbiota alter host histone acetylation and methylation in multiple tissues• Western diet suppresses microbiota-driven SCFA production and chromatin effects• SCFAs recapitulate microbiota-driven chromatin and transcriptional effects”
Gut bacteria found to trigger gene that protects against type 1 diabetes
“Researchers have discovered that a powerful guardian gene known to protect against a variety of autoimmune diseases, including type 1 diabetes, is triggered by the bacteria in our gut. This […]
Researchers see atrazine affecting health across generations
“Observations indicate that although atrazine does not promote disease in the directly exposed F1 [first] generation, it does have the capacity to promote the epigenetic transgenerational inheritance of disease in […]
How babies’ environments lead to poor health later
“research suggests that altering aspects of the nutritional, microbial and psychosocial environment early in development can leave lasting marks on the epigenome, with the potential to reduce levels of chronic […]
The Best Exercise for Aging Muscles
“Among the younger subjects who went through interval training, the activity levels had changed in 274 genes, compared with 170 genes for those who exercised more moderately and 74 for […]